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  • Title: [Massive iodine absorption after joint irrigation-suction drainage with PVP-iodine (betadine)].
    Author: Friederich N, Müller W.
    Journal: Z Unfallchir Versicherungsmed; 1992; 85(2):74-80. PubMed ID: 1467018.
    Abstract:
    Iodine is known as a local disinfectant substance for more than 100 years. Its use however was restricted due to strong local irritation. In the last 25 years Polyvinylpyrrolidon-Iodine solutions (Povidone-Iodine, PVP-Iodine, Betadine) has become more and more popular for treating traumatologic, surgical and orthopaedic infections. However several papers have reported changes in the blood chemistry (T3, T4, TSH, PBJ and Iodine excretion in the urine) after utilizing PVP-Iodine, especially in visceral surgery. We report on a patient in whom a massive iodine resorption with clinical signs of hyperthyroidism occurred, with soft tissue necrosis at the site of irrigation.
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