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  • Title: [The mechanism of action of chorionic gonadotropin on lactate dehydrogenase activity].
    Author: Zimin IuV, Solopaeva IM.
    Journal: Biull Eksp Biol Med; 1992 Jul; 114(8):217-8. PubMed ID: 1467501.
    Abstract:
    The purpose of this report is to demonstrate that chorionic gonadotropin (CG) interacts nonspecifically with lactate dehydrogenase changing its catalytic activity. The binding in vitro of CG (5 mg/ml) to the enzyme is accompanied by conformational changes of its protein and kinetic characteristics. It may be possible that chorionic gonadotropin exercises a controlling influence on lactate dehydrogenase activity in the cell.
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