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  • Title: Coupled folding during translation initiation.
    Author: Pestova TV, Hellen CU.
    Journal: Cell; 2003 Dec 12; 115(6):650-2. PubMed ID: 14675529.
    Abstract:
    The structure of the eukaryotic initiation factor eIF4E bound to a cognate domain of eIF4G and m(7)GDP in this issue of Cell shows that these factors undergo coupled folding to form a stable complex with high cap binding activity that promotes efficient ribosomal attachment to mRNA during translation initiation.
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