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  • Title: Intravitreal r-TPA and gas injection in traumatic submacular hemorrhage.
    Author: Holland D, Wiechens B.
    Journal: Ophthalmologica; 2004; 218(1):64-9. PubMed ID: 14688438.
    Abstract:
    AIM: To present the technique and efficiency of intravitreal recombinant tissue plasminogen activator (r-TPA) and gas injection in acute submacular hemorrhage (SMH) due to traumatic choroidal rupture. PATIENTS AND METHODS: 0.4 ml of sulfur hexafluoride was injected into the vitreous cavity in 2 patients with SMH due to traumatic choroidal rupture. In 1 patient gas injection was combined with 50 microg r-TPA. Both patients were closely followed. RESULTS: Preoperative visual acuity was 20/125 in one eye and 20/100 in the other. At the end of the follow-up, visual acuity had improved to 20/32 in both eyes. CONCLUSION: r-TPA and gas injection into the vitreous body may be an efficient therapy in patients with submacular hemorrhage due to choroidal rupture.
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