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  • Title: Pyoderma gangrenosum, polycythemia rubra vera, and the development of leukemia.
    Author: Ho KK, Otridge BW, Vandenberg E, Powell FC.
    Journal: J Am Acad Dermatol; 1992 Nov; 27(5 Pt 2):804-8. PubMed ID: 1469131.
    Abstract:
    A patient with long-standing, well-controlled polycythemia rubra vera developed recurrent episodes of bullous pyoderma gangrenosum followed by the transformation of his hematologic disease into a rapidly progressive acute myeloid leukemia. This case, together with previously described patients, indicates that the appearance of bullous pyoderma gangrenosum in a patient with polycythemia rubra vera is often of ominous prognostic significance.
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