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Title: Aspermytin A: a new neurotrophic polyketide isolated from a marine-derived fungus of the genus Aspergillus. Author: Tsukamoto S, Miura S, Yamashita Y, Ohta T. Journal: Bioorg Med Chem Lett; 2004 Jan 19; 14(2):417-20. PubMed ID: 14698172. Abstract: A new polyketide, aspermytin A (1), was isolated from a cultured marine fungus, Aspergillus sp., which was separated from the mussel, Mytilus edulis. Its structure was elucidated on the basis of their spectral data, and the absolute configuration of 1 was determined by the CD spectrum. Aspermytin A induced neurite outgrowth in rat pheochromocytoma (PC-12) cells at concentration of 50 microM.[Abstract] [Full Text] [Related] [New Search]