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  • Title: [Significance of changes in plasma lipid peroxide levels in critically ill patients after liver transplantation].
    Author: Liu C, Zhou XS, Geng QM.
    Journal: Zhongguo Wei Zhong Bing Ji Jiu Yi Xue; 2004 Jan; 16(1):33-5. PubMed ID: 14706201.
    Abstract:
    OBJECTIVE: To investigate the relationship between plasma lipid peroxide (LPO) levels and prognosis in critically ill patients after liver transplantation. METHODS: Plasma LPO levels were measured in 18 patients within 21 days after liver transplantation, and their relations to the prognosis were analyzed. RESULTS: Plasma LPO levels were markedly elevated in patients before state of illness got severe, especially in those with fatal outcome. The peak LPO levels were much higher in non-survivors than in survivors, and mortality rate in patients whose plasma LPO exceeding 10 micromol/L (5/6 cases) was significantly higher than those under 10 micromol/L (1/12 cases, P<0.01). The mortality rate in patients with daily fluctuation range of plasma LPO levels over 1.2 micromol.L(-1).d(-1) was higher than those under 1.2 micromol.L(-1).d(-1), and the difference was significant between two groups (P<0.01). CONCLUSION: Measurement of plasma LPO level might be of clinical significance to properly judge the critically ill conditions, and it can be used as routine examination for patients after liver transplantation.
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