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  • Title: Mass spectrometric analysis of putative capa-gene products in Musca domestica and Neobellieria bullata.
    Author: Predel R, Russell WK, Tichy SE, Russell DH, Nachman RJ.
    Journal: Peptides; 2003 Oct; 24(10):1487-91. PubMed ID: 14706527.
    Abstract:
    Neuropeptides of the capa-gene are typical of the abdominal neurosecretory system of insects. In this study, we investigated these peptides in two widely distributed and large pest flies, namely Musca domestica and Neobellieria bullata. Using a combination of MALDI-TOF and ESI-QTOF mass spectrometry, periviscerokinins and a pyrokinin were analyzed from single perisympathetic organ preparations. The species-specific peptide sequences differ remarkably between the related dipteran species. These differences could make it possible to develop peptide-analogs with group- or species-specific efficacy.
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