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  • Title: Regulation of the c-Abl and Bcr-Abl tyrosine kinases.
    Author: Hantschel O, Superti-Furga G.
    Journal: Nat Rev Mol Cell Biol; 2004 Jan; 5(1):33-44. PubMed ID: 14708008.
    Abstract:
    The prototypic non-receptor tyrosine kinase c-Abl is implicated in various cellular processes. Its oncogenic counterpart, the Bcr-Abl fusion protein, causes certain human leukaemias. Recent insights into the structure and regulation of the c-Abl and Bcr-Abl tyrosine kinases have changed the way we look at these enzymes.
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