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  • Title: Reversible leg ulcer due to hydroxyurea in a case of chronic myeloid leukemia.
    Author: Tripathi AK, Ahmad R, Sawlani KK.
    Journal: J Assoc Physicians India; 2003 Oct; 51():1014-5. PubMed ID: 14719596.
    Abstract:
    The cutaneous side effects of hydroxyurea are lesser known complication of long term hydroxyurea therapy in myeloproliferative disorders. We report a non-diabetic patient, who developed hydroxyurea dermopathy (leg ulcers) during long-term treatment with hydroxyurea for chronic myeloid leukemia (CML). The time course of the development of ulcers and its healing suggests that these resulted from the direct toxicity of hydroxyurea. We aim to increase clinical awareness of this problem.
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