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  • Title: [Rosai-Dorfman disease with orbital and rhinopharyngeal localizations. A case report].
    Author: Ben Ghorbel I, Bouzaidi K, Chelaifa K, Kchir MN, Khanfir M, Trabelsi S, Lamloum M, Houman MH, Miled M.
    Journal: Ann Otolaryngol Chir Cervicofac; 2003 Nov; 120(5):308-12. PubMed ID: 14726851.
    Abstract:
    OBJECTIVES: We present a case report of Rosai-Dorfman disease with multiple extranodal involvement and favorable outcome after steroid therapy. MATERIAL AND METHODS: Rosai-Dorfman disease was diagnosed in a 17-year-old man with orbital, lacrymal, and rhinopharyngeal localizations. Histopathologic examination of lymphadenopathy biopsy revealed the diagnostic of Rosai-Dorfman disease. We present the histological findings leading to diagnosis and radiological data. RESULTS: Conservative treatment with oral steroids resulted in the resolution of cervical lymphadenopathy and extranodal lesions. The patient was free of problems nine mouths after discontinuation of his treatment, demonstrating its efficacy and safety. CONCLUSION: Rosai-Dorfman disease is a benign disorder and steroid treatment must be initiated in cases with significant cosmetic deformity.
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