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  • Title: [Pulmonary Infiltrate, Pleural Effusion and IgM Macroglobulinaemia].
    Author: Reichenberger F, Heberlein JU, Müller A, Wirtz H, Schauer J.
    Journal: Pneumologie; 2004 Jan; 58(1):33-5. PubMed ID: 14732898.
    Abstract:
    We report a 71-year-old mam with known IgM- Macroglobulinemia, who developed infiltrative pulmonary changes and a pleural effusion. Both, the pleural effusion and bronchoalveolar lavage revealed monoclonal IgM positive B-lymphocytoes. Transbronchial biopsies showed tissue infiltrates of lymphoplasmocytic cells, consistent with a pleuropulmonary manifestation of Morbus Waldenstroem. Bone marrow and gastrointestinal involvement could be excluded, and the diagnosis of a primary pulmonary immunocytoma was made. The patient underwent partial lung resection with removal of the affected lung tissue. Pleuropulmonary changes in patients with IgM-Macroglobulinaemia or Morbus Waldenstroem may be due to pulmonary involvement by the hematological disease.
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