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Title: A new anthracycline antibiotic, cinerubin R. Taxonomy, structural elucidation and biological activity. Author: Nakata M, Saito M, Inouye Y, Nakamura S, Hayakawa Y, Seto H. Journal: J Antibiot (Tokyo); 1992 Oct; 45(10):1599-608. PubMed ID: 1473987. Abstract: A novel anthracycline antibiotic, cinerubin R, was isolated from the fermentation broth of Streptomyces eurythermus strain H1715MY2. The structure of cinerubin R was elucidated to be 4"-aculosyl-4'-rhodinosyl-7-rhodosaminyl-epsilon-py rromycinone. Cinerubin R was active against Gram-positive bacteria and inhibited the growth of divergent multi-drug-resistant cells to the same extent as their parental cells.[Abstract] [Full Text] [Related] [New Search]