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  • Title: Split cord malformation and situs inversus totalis: case report and review of the literature.
    Author: Tubbs RS, Wellons JC, Oakes WJ.
    Journal: Childs Nerv Syst; 2005 Feb; 21(2):161-4. PubMed ID: 14745579.
    Abstract:
    INTRODUCTION: Situs inversus is a rare condition of visceral transposition in which the spinal axis is rarely affected. CASE REPORT: The authors report a patient with situs inversus totalis and Type II split cord malformation. The patient had no symptoms and presented with scoliosis. CONCLUSIONS: Recent compelling evidence from animal models and human case reports has lead to hypotheses that defects of the midline and laterality defects (e.g., situs inversus) are etiologically related. Confirmation from additional case reports of situs inversus and split cord malformation could prove useful in determining a genetic locus for split cord malformations or implicating various chemical agents that are known to produce situs inversus as potential causative factors in the production of split cord malformations.
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