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  • Title: Changes of urea-soluble and intrinsic membrane proteins in rat lenses during the formation of galactose cataract.
    Author: Zhao HR, Ren XH.
    Journal: Ophthalmic Res; 1992; 24(5):285-8. PubMed ID: 1475076.
    Abstract:
    Urea-soluble and intrinsic membrane proteins from normal and galactose cataractous rat lenses were analyzed by SDS-PAGE. During cataract formation, MP22 increased whereas MP26 decreased almost to nil and MP24 emerged. However, the relative amount of MP18 remained essentially unchanged. These results suggested a conversion of MP26 to MP22 during cataract formation. We also observed the changes in the relative abundance of the polypeptides of the urea-soluble fraction with cataractogenesis.
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