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  • Title: [Acute interstitial nephritis with oliguric renal failure following phenylbutazone medication].
    Author: Kuhlmann U, Fontana A, Briner J, Steinemann U, Siegenthaler W.
    Journal: Schweiz Med Wochenschr; 1978 Apr 01; 108(13):494-9. PubMed ID: 147510.
    Abstract:
    Acute oliguric renal failure due to acute interstitial nephritis developed in a patient after treatment with phenylbutazone. The histological, immuno-histological and serological features in this case are compatible with the involvement of a delayed hypersensitivity reaction in the pathogenesis of this drug-induced interstitial nephritis. Other side effects of phenylbutazone on the kidney and the water and electrolyte metabolism are discussed.
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