These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Thermal denaturation of a helicoidal DNA model.
    Author: Barbi M, Lepri S, Peyrard M, Theodorakopoulos N.
    Journal: Phys Rev E Stat Nonlin Soft Matter Phys; 2003 Dec; 68(6 Pt 1):061909. PubMed ID: 14754236.
    Abstract:
    We study the static and dynamical properties of DNA in the vicinity of its melting transition, i.e., the separation of the two strands upon heating. The investigation is based on a simple mechanical model which includes the helicoidal geometry of the molecule and allows an exact numerical evaluation of its thermodynamical properties. Dynamical simulations of long-enough molecular segments allow the study of the structure factors and of the properties of the denaturated regions. Simulations of finite chains display the hallmarks of a first order transition for sufficiently long-ranged stacking forces although a study of the model's "universality class" strongly suggests the presence of an "underlying" continuous transition.
    [Abstract] [Full Text] [Related] [New Search]