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Title: Chronic myeloid leukemia with an e13a3 BCR-ABL fusion: benign course responsive to imatinib with an RT-PCR advisory. Author: Snyder DS, McMahon R, Cohen SR, Slovak ML. Journal: Am J Hematol; 2004 Feb; 75(2):92-5. PubMed ID: 14755375. Abstract: A case of a patient with chronic myeloid leukemia whose cells expressed an e13a3 (b2a3) variant BCR-ABL p210 mRNA is presented. The variant splice was detected by a qualitative reverse transcriptase polymerase chain reaction using primers complementary to BCR exon 13 (b2) and ABL exon 3 (a3). The patient responded well to imatinib and achieved a complete cytogenetic response.[Abstract] [Full Text] [Related] [New Search]