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  • Title: Evolutionary innovation of the excretory system in Caenorhabditis elegans.
    Author: Wang X, Chamberlin HM.
    Journal: Nat Genet; 2004 Mar; 36(3):231-2. PubMed ID: 14758362.
    Abstract:
    The evolution of complexity relies on changes that result in new gene functions. Here we show that the unique morphological and functional features of the excretory duct cell in C. elegans result from the gain of expression of a single gene. Our results show that innovation can be achieved by altered expression of a transcription factor without coevolution of all target genes.
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