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  • Title: Magnetic resonance imaging in the diagnosis and local staging of primary bone tumors.
    Author: Rafique MZ, Bari V.
    Journal: J Coll Physicians Surg Pak; 2004 Jan; 14(1):10-3. PubMed ID: 14764253.
    Abstract:
    OBJECTIVE: To evaluate relationship of magnetic resonance (MR) imaging in the diagnosis and local staging of primary bone tumors with histopathological and surgical outcome. DESIGN: Cross-sectional comparative study. PLACE AND DURATION OF STUDY: Radiology Department, The Aga Khan University Hospital, Karachi from December 1999 to March 2002. SUBJECTS AND METHODS: Thirty patients suspected of having primary bone tumors were selected. MRI scans were evaluated for local staging including intramedullary tumor length, cortical, soft tissue, neuro-vascular, joint and epiphyseal involvement. MR staging was compared with surgical and pathological staging and MR diagnosis with histopathological diagnosis considering benign and malignant tumors and specific diagnosis. RESULTS: The study included 30 patients with age ranging from 5 - 75 years (mean 30.1 years). Twenty-three patients had malignant and 7 benign tumors. On MRI, 25 tumors were characterized as malignant and 2 tumors were false positive for malignancy. CONCLUSION: MR imaging proved to be accurate in local staging of bone tumors and determination of the extent of disease in benign tumors.
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