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  • Title: New halimane diterpenoids from Croton oblongifolius.
    Author: Roengsumran S, Pornpakakul S, Muangsin N, Sangvanich P, Nhujak T, Singtothong P, Chaichit N, Puthong S, Petsom A.
    Journal: Planta Med; 2004 Jan; 70(1):87-9. PubMed ID: 14765304.
    Abstract:
    Three new halimane-type diterpenoids, crotohalimaneic acid ( 1), crotohalimoneic acid ( 2) and 12-benzoyloxycrotohalimaneic acid ( 3), were isolated from the stem bark of Croton oblongifolius Roxb. Their structures were established on the basis of spectroscopic and X-ray analysis. Compounds 1 and 2 showed non-specific strong cytotoxicity against a panel of human tumor cell lines; whereas 3 was inactive.
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