Title: [Pathogenic factor (Dampness-heat) of glomerulopathy]. Author: Yu JY, Xiong NN. Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi; 1992 Aug; 12(8):458-60, 451. PubMed ID: 1477499. Abstract: Mesangial proliferative glomerulonephritis (MsPGN) induced by chronic serum sickness in rabbits coincide with the human chronic progressive glomerulonephritis resulted from repeated infection, which is similar to pathologic changes of Dampness-Heat Syndrome. The experimental model of MsPGN was treated by Abelmoschus manihot. which could remove the Dampness-Heat. The amount of proteinuria in treating and control group were 62.68mg/24hr and 121.94mg/24hr respectively (P < 0.05), the number of cells in glomeruli were 61.54 and 80.39 respectively (P < 0.01), and diameters of glomeruli were 102.43 microns and 121.13 microns respectively (P < 0.01). It suggested that the drug could alleviate circulating immune complex (CIC) mediated renal injury.[Abstract] [Full Text] [Related] [New Search]
