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  • Title: Limiting applications of cryotherapy for severe retinopathy of prematurity.
    Author: Spencer R, Hutton WL, Snyder WB, Fuller DG, Fish GE, Vaiser A, Jost BF.
    Journal: Ophthalmic Surg; 1992 Nov; 23(11):766-9. PubMed ID: 1484670.
    Abstract:
    In an effort to minimize surgical and visual morbidity of cryotherapy for retinopathy of prematurity (ROP), 18 eyes of 13 patients with 3 to 7 clock hours of stage 3 ROP with "plus" disease were treated by cryotherapy applications limited to the avascular retina adjacent to the areas of stage 3 disease. In 17 of 18 eyes, this limited use of cryotherapy was sufficient to cause regression of ROP without further treatments. After at least 3 months follow-up, ROP outcome showed a normal macular appearance in 16 eyes; two eyes developed macular dragging; no retinal detachments occurred.
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