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  • Title: Mycoplasma gallisepticum vaccination-challenge: an egg-production model.
    Author: Evans RD, Hafez YS, Orthel FW.
    Journal: Avian Dis; 1992; 36(4):956-63. PubMed ID: 1485879.
    Abstract:
    Specific-pathogen-free layer hens in maximum lay were exposed by aerosol to a broth culture of Mycoplasma gallisepticum R' strain. Egg-production loss of greater than 50% was evident 7-14 days following challenge of unvaccinated chickens, with a gradual recovery during the next several days. Various vaccine preparations were tested to determine the effect in the model. All vaccinated chickens exhibited significantly (P < or = 0.05) lower egg-production loss than the unvaccinated controls. The model provides a method for testing treatment effects on egg-production losses resulting from controlled exposure to M. gallisepticum and may be useful in simulating field exposure.
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