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  • Title: [Allogeneic bone marrow transplantation in myeloid leukemia: chemical conditioning, clinical course and results].
    Author: Glejzer O, Sedzimirska M, Tomaszewska-Toporska B, Tomeczko J, Kołodziej J, Pacuszko T, Was A, Bocheńska J, Jaźwiec B, Klimczak A.
    Journal: Acta Haematol Pol; 1992; 23(2 Suppl 1):49-59. PubMed ID: 1488872.
    Abstract:
    10 patients between the ages of 5 and 40 yrs with myeloid leukemia (4 acute, 6 chronic) in early (5 cases) or intermediate stage of the disease were given Cyclophosphamide and Busulfan (6 cases) or Cyclophosphamide, Busulfan and VP-16 (4 cases with CML) and bone marrow transplants from HLA-matched donors (in 9 cases from siblings and in one case from HLA phenotypically matched father). There was one transplant related death and 3 relapses in CML cases. In cases which relapsed GvHD was not observed. Altogether acute GvH and chronic GvHD was seen in 2 and 4 cases, respectively. All grafted cases with AML survive in continuous remission lasting more than 2 years (median 30.5 month).
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