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Title: In vitro activity of Ro 23-9424 against clinical isolates of Legionella species. Author: Edelstein PH, Edelstein MA. Journal: Antimicrob Agents Chemother; 1992 Nov; 36(11):2559-61. PubMed ID: 1489206. Abstract: Agar and broth microdilution MICs of Ro 23-9424 that inhibited 90% of 22 Legionella clinical isolates tested were 0.64 and 0.08 micrograms/ml, respectively; respective erythromycin values were 1.0 and 0.12 micrograms/ml. Ro 23-9424 (1 microgram/ml) was slightly more active than the same erythromycin concentration in a macrophage system, for both Legionella pneumophila strains studied.[Abstract] [Full Text] [Related] [New Search]