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  • Title: Rapid stimulatory effect of bradykinin on glucose transport across the brush-border and basolateral membranes of rat jejunal enterocytes.
    Author: Sharp PA, Debnam ES.
    Journal: Exp Physiol; 1992 Nov; 77(6):913-6. PubMed ID: 1489546.
    Abstract:
    Bradykinin has been shown to stimulate sugar uptake by intact intestine, but the cellular locus of this action is unknown. In this study on rat we show that bradykinin (10(-7) M) stimulates both sodium-dependent glucose uptake at the brush-border membrane and carrier-mediated movement across the basolateral membrane of upper villus enterocytes. These results suggest a role for bradykinin in the local control of glucose transport though the mechanisms underlying these effects have still to be elucidated.
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