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  • Title: Effect of ethylene glycol on transcription of Neurospora crassa conidial genome.
    Author: Chaudhuri RK.
    Journal: Experientia; 1978 Jun 15; 34(6):735-6. PubMed ID: 149018.
    Abstract:
    Ethylene glycol (EG) was found not to alter DNA sequences in Neurospora crassa conidia, though it is believed to be mutagenic in nature. Molecular hybridization revealed 20% increase in whole RNA transcripts in EG-treated conidia, which indicates that while untreated conidia increase RNA synthesis by 2.35fold, treated conidia are inhibited and undergo only a 1.2fold increase. Thus there is an inhibition in potential RNA synthesis, though some RNA synthesis goes on in presence of ethylene glycol.
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