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  • Title: [Assessment of vitamin B2, B6, and PP supply from data on excretion of vitamins and their metabolites in alimentary iron and riboflavin deficiency].
    Author: Alekseeva IA, Kodentsova VM, Vrzhesinskaia OA, Zvereva TE, Khotimchenko SA, Spirichev VB.
    Journal: Vopr Med Khim; 1992; 38(5):17-20. PubMed ID: 1492387.
    Abstract:
    Alimentary deficiency in riboflavin and/or iron in rats involved distinct decrease in excretion of 4-pyridoxylic acid and 1-N-methyl nicotinamide--the metabolites considered as the indices of vitamins B6 and PP consumption. The effect observed appears to occur due to a decrease in activity of some iron- and flavin-containing enzymes participating in the metabolism of pyridoxine and niacin. Addition to the diet of the deficient component normalized these patterns. Use of the data on excretion of 4-pyridoxylic acid and 1-N-methyl nicotinamide as criteria of consumption of pyridoxine and niacin is discussed.
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