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  • Title: [Changes in thrombocytapheresis concentrations caused by leukocyte depletion with polyester filters].
    Author: Weisbach V, Riess H, Gindi N, Zeiler T, Riewald M, Zingsem J, Eckstein R.
    Journal: Infusionsther Transfusionsmed; 1992 Jun; 19(3):146-8. PubMed ID: 1498557.
    Abstract:
    We studied platelet loss, leukocyte depletion, T/B-cell-ratio, platelet morphology and platelet function (aggregation, hypotonic shock reaction, retention and retraction) prior to and after filtration through two different polyester filters (Sepacell PL-5A, Pall PL100) as well as the posttransfusional platelet increment 1 h after transfusion in 8 pairs of single donor platelet concentrates (Cobe Spectra, Fresenius AS 104). Leukocyte depletion was effective (greater than 99.9%) and platelet loss acceptable in both filters, all tests showing no indication of a diminished platelet function by filtration.
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