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  • Title: Severe hypertension and massive proteinuria in a newborn with renal artery stenosis.
    Author: Cachat F, Bogaru A, Micheli JL, Lepori D, Guignard JP.
    Journal: Pediatr Nephrol; 2004 May; 19(5):544-6. PubMed ID: 14986083.
    Abstract:
    Renal vein thrombosis and the congenital nephrotic syndrome have been associated with nephrotic-range proteinuria/nephrotic syndrome and hypertension in the newborn period. We describe a newborn with severe hypertension and proteinuria secondary to unilateral renal artery stenosis. Proteinuria completely disappeared with blood pressure control (with sodium nitroprusside and an angiotensin-converting enzyme inhibitor). Although renin was not measured, we speculate that proteinuria might have been induced by a high renin state, and was controlled by the angiotensin-converting enzyme inhibitor.
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