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  • Title: Biomimetic studies on anti-thyroid drugs and thyroid hormone synthesis.
    Author: Roy G, Nethaji M, Mugesh G.
    Journal: J Am Chem Soc; 2004 Mar 10; 126(9):2712-3. PubMed ID: 14995183.
    Abstract:
    The selenium analogues of anti-thyroid drugs exhibit their anti-thyroid action by a mechanism different from that of MMI. The selenium analogue of MMI and related selenium compounds exhibit high GPx activity, providing a novel method for the reversible inhibition of thyroid hormone biosynthesis.
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