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  • Title: Rat liver BiP/GRP78 is down-regulated by a peroxisome-proliferator, clofibrate.
    Author: Motojima K, Goto S.
    Journal: FEBS Lett; 1992 Aug 17; 308(2):207-10. PubMed ID: 1499732.
    Abstract:
    Administration of clofibrate in rat results in down-regulation of several liver proteins and a vast induction of peroxisomal proteins. One protein was identified as BiP/GRP78 using antibodies and cDNA cloning. The level of mRNA was reduced by the drug.
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