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  • Title: Effect of 2-chlorodeoxyadenosine therapy on bone marrow fibrosis in hairy cell leukemia.
    Author: Dedic K, Zák P.
    Journal: Neoplasma; 2004; 51(1):56-8. PubMed ID: 15004661.
    Abstract:
    The study shows the influence of 2-chlorodeoxyadenosine therapy on bone marrow fibrosis in patients with hairy cell leukemia. Eighteen patients were studied; bone marrow fibrosis was graded 0-4 according to the quantity and pattern of distribution of reticulin. The grade of bone marrow fibrosis was established before the therapy and then in 12- and 24-month intervals. Patients showed complete remission after the therapy and remarkable reduction of bone marrow fibrosis.
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