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  • Title: [The effectiveness of Mycobacteria tuberculosis isolation by polymerase chain reaction: results of a randomized trial].
    Author: Vladimirskiĭ MA, Shipina LK, Levchenko MV.
    Journal: Probl Tuberk Bolezn Legk; 2003; (12):28-30. PubMed ID: 15004969.
    Abstract:
    The results of testing sputum for Mycobacterium tuberculosis by different methods: polymerase chain reaction (PCR), luminescence microscopy, and culture tests were compared. Clinical sputum samples were studied in 62 patients with pulmonary tuberculosis and 72 patients with non-specific diseases of the lung. The specificity of PCR was 98.7%. The sensitivity of PCR was 59.6%; that of cultural tests was 43.8%.
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