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  • Title: Ginkgo biloba promotes short-term retention of spatial memory in rats.
    Author: Hoffman JR, Donato A, Robbins SJ.
    Journal: Pharmacol Biochem Behav; 2004 Mar; 77(3):533-9. PubMed ID: 15006464.
    Abstract:
    This study examines possible interactions between exposure to Ginkgo biloba extract and enriched environments on the acquisition and retention of spatial learning following massed and spaced trials. After 4 weeks of exposure to either ginkgo or vehicle, 8-week-old rats were tested using a Morris Water Maze in either massed or spaced trials. While ginkgo did not have an effect on maze acquisition or long-term retention, it did promote short-term retention of spatial memory. Following reversal training, ginkgo promoted short-term retention for two groups but impaired retention for a third. These results suggest that ginkgo has powerful effects on short-term retention that vary with training conditions.
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