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  • Title: Cutaneous seeding of hepatocellular carcinoma due to percutaneous ethanol injection and masquerading as a pyogenic granuloma.
    Author: Lee MC, Huang YL, Yang CH, Kuo TT, Hong HS.
    Journal: Dermatol Surg; 2004 Mar; 30(3):438-40. PubMed ID: 15008879.
    Abstract:
    BACKGROUND: This investigation reports a 68-year-old man with a history of hepatocellular carcinoma (HCC) diagnosed 2 years previously who developed a single, easy-bleeding, pyogenic granuloma (PG)-like lesion on his right upper abdomen, located in the area of previous therapeutic percutaneous ethanol injection (PEI) for HCC treatment. The lesion developed 3 months after the injection. The tumor was found to be identical to his previous HCC. OBJECTIVE: To describe a case of cutaneous seeding of HCC during PEI presented as a PG-like lesion. To our knowledge, this is the first such case reported in the literature. METHODS: This is a case report and review the literature. RESULTS: Immunostainings for alpha-fetoprotein and hepatocyte monoclonal antibody confirmed the diagnosis. Besides, the patient had no other metastatic lesion. CONCLUSION: This tumor is believed to be caused by cutaneous seeding of HCC during PEI and is simulated clinically as a PG.
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