These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Spikes on the postoperative EEG are related to preoperative spike frequency and postoperative seizures.
    Author: Janszky J, Schulz R, Hoppe M, Ebner A.
    Journal: Epilepsy Res; 2003 Dec; 57(2-3):153-8. PubMed ID: 15013056.
    Abstract:
    PURPOSE: To investigate the factors which influence the persistence of interictal epileptiform discharges (IED) after epilepsy surgery. METHODS: In this retrospective study we included patients with intractable medial temporal lobe epilepsy (MTLE) who underwent presurgical evaluation including high-resolution MRI and video-EEG monitoring with seizure registration prior to an anterior temporal lobe resection. The postsurgical outcome was assessed by our team 6 months and 2 years after the surgery. RESULTS: One hundred and forty-seven patients fulfilled the inclusion criteria. The mean age of the patients was 31.8 (range 16-59 years). In 22 patients (15%) interictal epileptiform discharges were present on the postoperative routine EEG. We found that both the preoperative spike frequency ( P < 0.001 ) and postoperative seizures ( P = 0.04 ) were independently associated with the presence of IED on the postoperative routine EEG. The preoperative spike frequency was not associated with the postoperative outcome. The extent of resection showed no influence on the presence of postoperative IED. CONCLUSION: We hypothesize that two factors independently influence the presence of postoperative spikes: chronic interictal disturbance (represented as preoperative spike frequency) and the acute (postoperative) seizures. Our study confirmed that persistent postoperative IED had a prognostic value regarding the outcome of the epilepsy surgery.
    [Abstract] [Full Text] [Related] [New Search]