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  • Title: [Expression of testosterone in the rapid growing rat condylar cartilage and the expression changes after the function mandibular advancement].
    Author: Li XB, Chen KY, Zhou Z, Luo SJ.
    Journal: Hua Xi Kou Qiang Yi Xue Za Zhi; 2004 Feb; 22(1):29-31. PubMed ID: 15017694.
    Abstract:
    OBJECTIVE: To investigate the expressions of Testosterone in the condylar cartilage of rapid growing rats. METHODS: The mimic functional appliances were used in experiment groups and rats were killed after 3 days, 1 week, 2 weeks, 3 weeks and 4 weeks. Immunohistochemical technique was used to detect the expression of T. RESULTS: T was expressed throughout the condylar cartilage. The Highest expressions were in mature layers of both experiment and control groups. Along with the maturation, the expressions of T in the condylar cartilage were changed respectively, and the immunostain levels in the mature layer of experiment groups 2 and 3 weeks were higher than those of control groups (P < 0.05). CONCLUSION: 1. T is a member of cartilage growth and development control system. 2. The orthopedic mechanism of functional appliance may be conducted by T.
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