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  • Title: Allogeneic bone marrow transplantation with non-T-cell-depleted marrow from two HLA-antigen-mismatched related donors.
    Author: Ogawa H, Ikegame K, Kawakami M, Taniguchi Y, Oka Y, Kawase I.
    Journal: Haematologica; 2004 Mar; 89(3):373-5. PubMed ID: 15020286.
    Abstract:
    Allogeneic BMT from 2 antigen-mismatched donors has been difficult to perform without T-cell depletion. Seven patients with advanced-stage hematologic malignancies underwent BMT with intensified graft-versus-host disease prophylaxis consisting of tacrolimus, methotrexate, and methylprednisolone. No rejection or acute GVHD >or= grade III was observed. This preliminary result is very promising.
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