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  • Title: Investigation of frequency of active Borna disease virus infection in Scottish blood donors.
    Author: Davidson F, Lycett C, Petrik J, Fazakerley JK.
    Journal: Vox Sang; 2004 Feb; 86(2):148-50. PubMed ID: 15023186.
    Abstract:
    BACKGROUND AND OBJECTIVES: Borna disease virus (BDV) can infect a wide range of vertebrate species causing neurological disease. In order to ensure the safety of blood supplies, it is essential to monitor blood for emerging pathogens. MATERIALS AND METHODS: One-hundred individual white cell pellets and pools representing 25 000 plasma donations from human blood were screened for BDV by reverse transcription-polymerase chain reaction (RT-PCR). RESULTS: BDV RNA was not detected in any of the samples. CONCLUSIONS: The results indicate that BDV is not widely spread in the UK human population and does not represent a risk as a transfusion-transmitted agent.
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