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  • Title: Cellular immunity to P. acnes in the normal population and patients with acne vulgaris.
    Author: Gowland G, Ward RM, Holland KT, Cunliffe WJ.
    Journal: Br J Dermatol; 1978 Jul; 99(1):43-7. PubMed ID: 150284.
    Abstract:
    Patients with varying degrees of acne, acne-free adult controls and samples of cord blood were investigated for cell mediated immunity to P. acnes using a leukocyte migration inhibition test. Despite the fact that the mean migration index tended to decrease with acne severity, only the patients with severe acne showed cell-mediated immunity. It is suggested that when cellular immunity arises it is a late event which may contribute to inflammation but is probably not a factor in its initiation.
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