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Title: Inhibition of mast cell-dependent immediate-type hypersensitivity reactions by purple bamboo salt. Author: Shin HY, Na HJ, Moon PD, Shin T, Shin TY, Kim SH, Hong SH, Kim HM. Journal: J Ethnopharmacol; 2004 Mar; 91(1):153-7. PubMed ID: 15036482. Abstract: Purple bamboo salt is a specially processed salt according to the traditional recipe using normal salt and bamboo etc. It has been used as a folk medicine for the purpose of prevention and treatment of various diseases in Korea. This report describes an inhibitory effect of purple bamboo salt on mast cell-mediated immediate-type allergic reactions. Purple bamboo salt (0.01-1 microg per site) significantly inhibited the ear swelling response induced by intradermal injection of compound 48/80 in mice. Purple bamboo salt (0.01-1 mg/ml) dose-dependently inhibited the histamine release from the rat peritoneal mast cells (RPMCs) by compound 48/80. Purple bamboo salt (0.01-1 g/kg) also dose-dependently inhibited the passive cutaneous anaphylaxis (PCA) by oral administration. Our results provide evidence that purple bamboo salt will be beneficial in the regulation of immediate-type of allergic reactions.[Abstract] [Full Text] [Related] [New Search]