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  • Title: Synthesis of 4-formyl-4-imidazolin-2-one nucleosides, isomers of uridine and 2'-deoxyuridine.
    Author: Jiang XJ, Kalman TI.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2004; 23(1-2):307-16. PubMed ID: 15043156.
    Abstract:
    The syntheses of the ribo- and deoxyribonucleoside derivatives of 4-formyl-4-imidazolin-2-one, isosteric isomers of uridine and 2'-deoxyuridine, respectively, were carried out by ring contraction of the corresponding 5-bromouracil nucleosides, followed by conversion of the carboxyl side-chain of the products to the respective carboxaldehyde derivatives.
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