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  • Title: Meningioma developed 25 years after radiation therapy for Cushing's disease.
    Author: Tsukamoto H, Yoshinari M, Okamura K, Ishitsuka T, Fujishima M.
    Journal: Intern Med; 1992 May; 31(5):629-32. PubMed ID: 1504425.
    Abstract:
    A 44-year-old woman who had been therapeutically irradiated with 45 Gy to the sellar lesion for Cushing's disease has been in remission for 25 years. A large but asymptomatic brain tumor was accidentally found in the right middle fossa by a routine follow-up computed tomography. Upon surgical removal of the tumor, the histology revealed a fibroblastic meningioma. Although the incidence of meningioma following irradiation to pituitary adenoma is rare, a follow-up computed tomography should be taken to any possible late onset, and curable complication.
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