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  • Title: Apatite formation on non-woven fabric of carboxymethylated chitin in SBF.
    Author: Kokubo T, Hanakawa M, Kawashita M, Minoda M, Beppu T, Miyamoto T, Nakamura T.
    Journal: Biomaterials; 2004 Aug; 25(18):4485-8. PubMed ID: 15046939.
    Abstract:
    Chitin fibres constituting a non-woven fabric were carboxymethylated in monochloro acetic acid and treated with saturated Ca(OH)(2) aqueous solution. Within 3 days in a simulated body fluid with pH value and ion concentrations nearly equal to those of human blood plasma, a bonelike apatite layer formed on the surface of fibres of the treated fabric. The apatite-chitin fibre composite thus prepared is expected to be useful as a flexible bioactive bone-repairing material.
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