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  • Title: Production of L-phenylacetyl carbinol by immobilized cells of Saccharomyces cerevisiae.
    Author: Mandwal AK, Tripathi CK, Trivedi PD, Joshi AK, Agarwal SC, Bihari V.
    Journal: Biotechnol Lett; 2004 Feb; 26(3):217-21. PubMed ID: 15049366.
    Abstract:
    Conversion of benzaldehyde to L-phenylacetyl carbinol (L-PAC) was achieved with immobilized, growing cells of Saccharomyces cerevisiae in different reactors. Product formation increased (31%) with the subsequent initial reuses of the entrapped cells. Biomass production and PAC formation depleted (40 and 57%, respectively) after 4-5 continuous growth and biotransformation cycles. With the regeneration of the biocatalysts, catalytic activity of the cells was resumed. The highest yields were in a stirred tank reactor (29 g PAC) from 77 g benzeldehyde with 14 repeated uses of entrapped cells.
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