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Title: Synthesis of conformationally restricted 2,3-diarylbenzo[b]furan by the Pd-catalyzed annulation of o-alkynylphenols: exploring a combinatorial approach. Author: Hu Y, Nawoschik KJ, Liao Y, Ma J, Fathi R, Yang Z. Journal: J Org Chem; 2004 Apr 02; 69(7):2235-9. PubMed ID: 15049614. Abstract: The palladium/bpy-catalyzed annulation of o-alkynylphenol with various aryl halides to generate diversified 2,3-diarylbenzo[b]furan is herein described. This method provides an efficient synthetic pathway for the combinatorial synthesis of conformationally restricted 2,3-diarylbenzo[b]furan for drug discovery.[Abstract] [Full Text] [Related] [New Search]