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  • Title: Synthesis of conformationally restricted 2,3-diarylbenzo[b]furan by the Pd-catalyzed annulation of o-alkynylphenols: exploring a combinatorial approach.
    Author: Hu Y, Nawoschik KJ, Liao Y, Ma J, Fathi R, Yang Z.
    Journal: J Org Chem; 2004 Apr 02; 69(7):2235-9. PubMed ID: 15049614.
    Abstract:
    The palladium/bpy-catalyzed annulation of o-alkynylphenol with various aryl halides to generate diversified 2,3-diarylbenzo[b]furan is herein described. This method provides an efficient synthetic pathway for the combinatorial synthesis of conformationally restricted 2,3-diarylbenzo[b]furan for drug discovery.
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