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  • Title: [Structure and degradation property of the PVA-collagen complex drug membrane].
    Author: Liang Y, Liu LR, Zhang QQ.
    Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2004 Feb; 26(1):18-23. PubMed ID: 15052768.
    Abstract:
    OBJECTIVE: To investigate the structure and degradation property of the polyvinyl alcohol (PVA)-collagen complex drug membrane. METHODS: Drug collagen membrane was complexed with PVA. The physical and chemical properties of the membrane were characterized by transmission electron microscopy, scanning electron microscope, forier transform-infrared spectroscopy and differential scanning calorimetry. Degradation experiment was performed to determine the degradation property of membrane and a degradation curve was therefor drawn. RESULTS: The thermodynamic stability of collagen membrane was not destroyed by adding PVA. Collagen had good compatibility with PVA. Compared with collagen membrane, collagen-PVA complex membrane had smaller and evener pores. Adding PVA decreased the degradation rate of membrane. CONCLUSIONS: PVA-collagen membrane has better microstructure and antidegradation property than collagen membrane.
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