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  • Title: Comparison of acute low-tone sensorineural hearing loss versus Meniere's disease by electrocochleography.
    Author: Noguchi Y, Nishida H, Tokano H, Kawashima Y, Kitamura K.
    Journal: Ann Otol Rhinol Laryngol; 2004 Mar; 113(3 Pt 1):194-9. PubMed ID: 15053200.
    Abstract:
    To clarify the pathogenesis of acute low-tone sensorineural hearing loss (ALHL), we retrospectively compared the electrocochleographic findings from 20 patients with ALHL with those from 58 patients with Meniere's disease (MD) classified into 4 groups (MD1 through MD4) according to their pure tone average. The mean summating potential-action potential ratio in the ALHL group was 0.35 +/- 0.13, which was significantly higher than the control ratio but similar to the ratio seen in the MD1 group (pure tone average < 25 dB hearing level). The mean detection threshold of the cochlear microphonics in the ALHL group was 32.0 +/- 9.4 dB normal hearing level, which was again similar to that seen in the MDI group. Moreover, more than 50% of patients with ALHL had normal cochlear microphonics input-output curves. We therefore conclude that the pathogenesis of ALHL arises from an endolymphatic hydrops with little or no impairment of hair cells that resembles early-stage MD.
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